Orally Disintegratng Tablets: A Recent Advancment

Abstract

The oral route is the most common and easily administered the
various types of dosage forms like tablets, capsules, syrups,
suspensions, elixirs etc. but some patients facing the difficulties
to swallow of these formulations.In terms of formulation, a orally
disintegrating tablet (ODT) differ from an conventional tablet by
modification of normal disintegrants with a superdisintegrant
which is highly sensitive to aqueous environment (saliva)
and disintegrates in fraction of time enhancing disintegration
followed by immediate dissolution .This unique property helps
rapid onset of action, avoid chocking, no water requirement,
pleasing mouth feel, avoid first pass metabolism .The present
review depicts various aspects of ODT‟s formulation, selection
of superdisintegrants, conventional technologies.